Nos publications

La qualité des travaux de recherche publiés par notre laboratoire au cours des 15 dernières années se reflète par l’envergure et la nature multidisciplinaire de nos études. En conséquence, la publication de nos travaux dans des revues de premier plan telles que Molecular Cell, Genes & Development, Nature Structural & Molecular Biology, Cell Reports, PLoS Genetics et Nature Communications est une indication claire de l’importance exceptionnelle de nos découvertes et de l’ampleur de nos contributions à la recherche.
Octobre 2021

Fission yeast proteins Puf2 and Puf4 are involved in repression of frp1 expression in response to iron

Beadoin, J., Normant, V., Brault, A., Henry, DJ., Bachand, F., Massé, E., Chua, G., and S. Labbé (2021). Molecular Microbiology. In press.

Juillet 2021

Co-transcriptional RNA cleavage by Drosha homolog Pac1 triggers transcription termination in fission yeast

Yague-Sanz, C., M. Duval, M. Larochelle and F. Bachand (2021). Nucleic Acids Res.

Décembre 2020

PDCD2 functions as an evolutionarily conserved chaperone dedicated for the 40S ribosomal protein uS5 (RPS2)

Landry-Voyer, A. M., D. Bergeron, C. Yague-Sanz, B. Baker and F. Bachand (2020). Nucleic Acids Res, 48: 12900-12916.

Juillet 2020

Nutrient-dependent control of RNA polymerase II elongation rate regulates specific gene expression programs by alternative polyadenylation

Yague-Sanz, C., Y. Vanrobaeys, R. Fernandez, M. Duval, M. Larochelle, J. Beaudoin, J. Berro, S. Labbe, P. E. Jacques and F. Bachand (2020). Genes Dev 34: 883-897.

Août 2019

Senataxin homologue Sen1 is required for efficient termination of RNA polymerase III transcription.

Rivosecchi, J., M. Larochelle, C. Teste, F. Grenier, A. Malapert, E. P. Ricci, P. Bernard, F. Bachand and V. Vanoosthuyse (2019). EMBO J 38: e101955.

Mai 2019

Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast.

Larochelle, M., D. Bergeron, B. Arcand and F. Bachand (2019). J Cell Sci 132.

Février 2019

The 40S ribosomal protein uS5 (RPS2) assembles into an extra-ribosomal complex with human ZNF277 that competes with the PRMT3-uS5 interaction.

Dionne, K. L., D. Bergeron, A. M. Landry-Voyer and F. Bachand (2019). J Biol Chem 294: 1944-1955.

Novembre 2018

Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome

Telekawa, C., F. M. Boisvert and F. Bachand (2018). Nucleic Acids Res 46: 11169-11183.

Octobre 2018

Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast

Larochelle, M., M. A. Robert, J. N. Hebert, X. Liu, D. Matteau, S. Rodrigue, B. Tian, P. E. Jacques and F. Bachand (2018). Nat Commun 9: 4364.

Septembre 2018

Long noncoding RNA repertoire and targeting by nuclear exosome, cytoplasmic exonuclease, and RNAi in fission yeast

Atkinson, S. R., S. Marguerat, D. A. Bitton, M. Rodriguez-Lopez, C. Rallis, J. F. Lemay, C. Cotobal, M. Malecki, P. Smialowski, J. Mata, P. Korber, F. Bachand and J. Bahler (2018). RNA 24: 1195-1213.

Octobre 2017

Comparative analysis of alternative polyadenylation in S. cerevisiae and S. pombe

Liu, X., M. Hoque, M. Larochelle, J. F. Lemay, N. Yurko, J. L. Manley, F. Bachand and B. Tian (2017). Genome Res 27: 1685-1695.

Mai 2017

Polyadenylation site selection: linking transcription and RNA processing via a conserved carboxy-terminal domain (CTD)-interacting protein

Larochelle, M., J. Hunyadkurti and F. Bachand (2017). Curr Genet 63: 195-199.

Février 2017

Multiple Transcriptional and Post-transcriptional Pathways Collaborate to Control Sense and Antisense RNAs of Tf2 Retroelements in Fission Yeast.

Mallet, P. L., M. Larochelle and F. Bachand (2017). Genetics 205: 621-632.

Novembre 2016

Human PDCD2L Is an Export Substrate of CRM1 That Associates with 40S Ribosomal Subunit Precursors

Landry-Voyer, A. M., S. Bilodeau, D. Bergeron, K. L. Dionne, S. A. Port, C. Rouleau, F. M. Boisvert, R. H. Kehlenbach and F. Bachand (2016).  Mol Cell Biol 36: 3019-3032.

Juillet 2016

The Nrd1-like protein Seb1 coordinates cotranscriptional 3' end processing and polyadenylation site selectio

Lemay, J. F., S. Marguerat, M. Larochelle, X. Liu, R. van Nues, J. Hunyadkurti, M. Hoque, B. Tian, S. Granneman, J. Bahler and F. Bachand (2016). Genes Dev 30: 1558-1572.

Décembre 2015

A Polyadenylation-Dependent 3' End Maturation Pathway Is Required for the Synthesis of the Human Telomerase RNA

Nguyen, D., V. Grenier St-Sauveur, D. Bergeron, F. Dupuis-Sandoval, M. S. Scott and F. Bachand (2015). Cell Rep 13: 2244-2257.

Décembre 2015

Fail-safe transcription termination: Because one is never enough

Lemay, J. F. and F. Bachand (2015). RNA Biol 12: 927-932.

Juillet 2015

Regulated Intron Retention and Nuclear Pre-mRNA Decay Contribute to PABPN1 Autoregulation

Bergeron, D., G. Pal, Y. B. Beaulieu, B. Chabot and F. Bachand (2015). Mol Cell Biol 35: 2503-2517.

Juin 2015

Widespread exon skipping triggers degradation by nuclear RNA surveillance in fission yea

Bitton, D. A., S. R. Atkinson, C. Rallis, G. C. Smith, D. A. Ellis, Y. Y. Chen, M. Malecki, S. Codlin, J. F. Lemay, C. Cotobal, F. Bachand, S. Marguerat, J. Mata and J. Bahler (2015). Genome Res 25: 884-896.

Octobre 2014

The RNA exosome promotes transcription termination of backtracked RNA polymerase II

Lemay, J. F., M. Larochelle, S. Marguerat, S. Atkinson, J. Bahler and F. Bachand (2014). Nat Struct Mol Biol 21: 919-926.

Décembre 2013

Poly(A) tail-mediated gene regulation by opposing roles of Nab2 and Pab2 nuclear poly(A)-binding proteins in pre-mRNA decay

Grenier St-Sauveur, V., S. Soucek, A. H. Corbett and F. Bachand (2013). Mol Cell Biol 33: 4718-4731.

Mars 2013

A proline-tyrosine nuclear localization signal (PY-NLS) is required for the nuclear import of fission yeast PAB2, but not of human PABPN1

Mallet, P. L. and F. Bachand (2013). Traffic 14: 282-294.

Novembre 2012

The THO complex cooperates with the nuclear RNA surveillance machinery to control small nucleolar RNA expression

Larochelle, M., J. F. Lemay and F. Bachand (2012). Nucleic Acids Res 40: 10240-10253.

Novembre 2012

Polyadenylation-dependent control of long noncoding RNA expression by the poly(A)-binding protein nuclear 1

Beaulieu, Y. B., C. L. Kleinman, A. M. Landry-Voyer, J. Majewski and F. Bachand (2012). PLoS Genet 8: e1003078.

Juin 2011

A Pre-mRNA degradation pathway that selectively targets intron-containing genes requires the nuclear poly(A)-binding protein

Lemieux, C., S. Marguerat, J. Lafontaine, N. Barbezier, J. Bahler and F. Bachand (2011). Mol Cell 44: 108-119.

Septembre 2010

Negative regulation of meiotic gene expression by the nuclear poly(a)-binding protein in fission yeast

St-Andre, O., C. Lemieux, A. Perreault, D. H. Lackner, J. Bahler and F. Bachand (2010). J Biol Chem 285: 27859-27868.

Mai-Juin 2010

Negative regulation of meiotic gene expression by the nuclear poly(a)-binding protein in fission yeast

Lemay, J. F., C. Lemieux, O. St-Andre and F. Bachand (2010). RNA Biol 7: 291-295.

Janvier 2010

The nuclear poly(A)-binding protein interacts with the exosome to promote synthesis of noncoding small nucleolar RNAs

Lemay, J. F., A. D’Amours, C. Lemieux, D. H. Lackner, V. G. St-Sauveur, J. Bahler and F. Bachand (2010). Mol Cell 37: 34-45.